The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
Feb. 24, 2014
Aurigene Discovery Technologies Limited, Bangalore, IN;
Um Pharmauji Sdn. Bhd, Kuala Lumpur, MY;
Siva Sanjeeva Rao Thunuguntla, Hyderabad, IN;
Subramanya Hosahalli, Bangalore, IN;
Satish Reddy Kunnam, Warangal, IN;
UM PHARMAUJI SDN. BHD., Kuala, Lumpur, MY;
AURIGENE DISCOVERY TECHNOLOGIES LIMITED, Bangalore, IN;
Abstract
The present invention provides trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitor compounds of formula (I), which may be therapeutically useful as DHODH inhibitors. wherein, R, Rand Rhave the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention in diseases or disorder, in particular their use in diseases or disorder where there is an advantage in inhibiting DHODH. The present invention also provides methods for synthesizing trisubstituted benzotriazole derivatives of formula (I). The present invention also provides pharmaceutical formulations comprising at least one of the DHODH inhibitor compound of formula (I) together with a pharmaceutically acceptable carrier, diluent or excipient.