The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
Jan. 11, 2016
Applicant:
Euticals S.p.a., Milan, IT;
Inventor:
Paride Grisenti, Milan, IT;
Assignee:
EUTICALS SPA, Milan, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/06 (2006.01); C12P 41/00 (2006.01); C12P 17/12 (2006.01); C12P 17/16 (2006.01);
U.S. Cl.
CPC ...
C07D 215/06 (2013.01); C12P 17/12 (2013.01); C12P 17/165 (2013.01); C12P 41/004 (2013.01);
Abstract
The present invention relates to the biocatalyzed synthesis of enantiomerically pure (3R) and (3S)-methyl-1,2,3,4-tetrahydroquinoline. Said enantiomerically pure compounds are useful as chiral synthons in organic synthesis and, in particular, for the preparation of diastereomerically pure (21R) and (21S)-agratroban and its analogs. New compounds used as intermediates in the process of the invention are also disclosed.