The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
May. 13, 2004
Etienne Duguet, Begles, FR;
Stéphane Mornet, Artigues Pres Boardeaux, FR;
Joseph Portier, Gradignan, FR;
Etienne Duguet, Begles, FR;
Stéphane Mornet, Artigues Pres Boardeaux, FR;
Joseph Portier, Gradignan, FR;
Abstract
The invention relates to aqueous dispersions, comprising particles based on a magnetic iron oxide with dimensions of ≦20 nm, the surface of which is modified by the grafting of aminated groups R with a covalent bonding to the surface of said particles, wherein the isoelectronic point of particles with such a modified surface is ≧10. The invention further relates to a method for production of said aqueous suspensions and a method for modification of the surface of the particles present in said dispersions, in particular, by the immobilisation of polysaccharides such as dextrans, particularly for the formulation of magnetic compositions which may be administered in vivo and in particular for the formulation of injectable compositions of contrast agents for MRI.