The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2017

Filed:

Jul. 20, 2012
Applicants:

Fabrizio Salvinelli, Rome, IT;

Beatrice Salvinelli, Rome, IT;

Emanuele Salvinelli, Rome, IT;

Alessandra D'eramo, Latina, IT;

Inventors:

Fabrizio Salvinelli, Rome, IT;

Beatrice Salvinelli, Rome, IT;

Emanuele Salvinelli, Rome, IT;

Alessandra D'Eramo, Latina, IT;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 15/08 (2006.01); A61K 31/4045 (2006.01); A61K 38/08 (2006.01); A61K 38/17 (2006.01); A61K 31/7004 (2006.01); A61K 33/00 (2006.01); A61K 33/04 (2006.01); A61K 33/14 (2006.01); A61K 31/727 (2006.01); A61K 38/18 (2006.01); A61M 15/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61M 15/08 (2013.01); A61K 9/0043 (2013.01); A61K 31/4045 (2013.01); A61K 31/7004 (2013.01); A61K 31/727 (2013.01); A61K 33/00 (2013.01); A61K 33/04 (2013.01); A61K 33/14 (2013.01); A61K 38/08 (2013.01); A61K 38/1709 (2013.01); A61K 38/185 (2013.01); A61M 15/009 (2013.01);
Abstract

The invention concerns a product consisting of distilled water or of an aqueous solution hypotonic or substantially isotonic with respect to blood plasma or, less preferably, hypertonic with respect to blood plasma, to be administered on the nasal mucosa according to a specific operation mode in order to cause an inflammation of an irritative kind, for use in a treatment of stimulation of the endogenous production of inflammatory mediators, in the therapy and prevention of neurological disorders, in particular of degenerative disorders of the central and peripheral nervous system. The inflammatory mediators the endogenous production of which is stimulated comprise NGF, neurotrophin-3, neurotrophin-4, serotonin, substance P, heparin, ECF-A.


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