The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
Mar. 22, 2012
Applicants:
Thomas S. Kupper, Belmont, MA (US);
Rahul Purwar, Arlington, MA (US);
Inventors:
Thomas S. Kupper, Belmont, MA (US);
Rahul Purwar, Arlington, MA (US);
Assignee:
THE BRIGHAM AND WOMEN'S HOSPITAL, INC., Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 45/00 (2006.01); A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 39/395 (2006.01); A61K 38/20 (2006.01); A61K 35/17 (2015.01); A61K 31/7088 (2006.01); A61K 31/7105 (2006.01); A61K 31/145 (2006.01); A61K 31/19 (2006.01); A61K 31/426 (2006.01); A61K 31/704 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/145 (2013.01); A61K 31/19 (2013.01); A61K 31/426 (2013.01); A61K 31/704 (2013.01); A61K 31/7088 (2013.01); A61K 31/7105 (2013.01); A61K 35/12 (2013.01); A61K 35/17 (2013.01); A61K 38/206 (2013.01);
Abstract
Described herein are methods for the treatment of cancer (e.g. melanoma, lung cancer, or other cancers). The methods involve administrating to a subject in need thereof an agonist of the IL-9 receptor (e.g. IL-9), e.g. an agent that binds and activates the IL-9 receptor, or an agent that increases IL-9 expression in the subject (e.g. administration of TH9 cells that express IL-9, or administration of an inhibitor of ROR).