The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
Dec. 30, 2014
The Hong Kong University of Science and Technology, Hong Kong, CN;
Nancy Yuk-Yu Ip, Hong Kong, CN;
Fanny Chui-Fun Ip, Hong Kong, CN;
Wing Yu Fu, Hong Kong, CN;
Guangmiao Fu, Hong Kong, CN;
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, Hong Kong, CN;
Abstract
Natural occurring inhibitors of cyclin-dependent protein kinase 5 (Cdk5), isolated from the root ofare structurally different from the known Cdk inhibitors. They show selectivity among different Cdks and efficacy to inhibit Cdk via a mixed-type of inhibition, which should lead to less toxicity and side-effects. They are useful in preventing and treating diseases and disorders associated with aberrant Cdk5 activities, such as acute and/or chronic pain, neuropathic pain, diabetes mellitus, cancer, neurodegenerative diseases and neuropathological disorders.