The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2017

Filed:

May. 29, 2012
Applicants:

Aaron Michels, Aurora, CO (US);

Maki Nakayama, Denver, CO (US);

David Ostrov, Gainesville, FL (US);

Inventors:

George Eisenbarth, Golden, CO (US);

Aaron Michels, Aurora, CO (US);

Maki Nakayama, Denver, CO (US);

David Ostrov, Gainesville, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/53 (2006.01); A61K 31/519 (2006.01); A61K 31/221 (2006.01); A61K 31/4409 (2006.01); A61K 31/4164 (2006.01); A61K 31/495 (2006.01); A61K 31/397 (2006.01); A61K 31/155 (2006.01); A61K 31/195 (2006.01); A61K 31/34 (2006.01); A61K 31/427 (2006.01); A61K 45/06 (2006.01); A61K 31/64 (2006.01);
U.S. Cl.
CPC ...
A61K 31/53 (2013.01); A61K 31/155 (2013.01); A61K 31/195 (2013.01); A61K 31/221 (2013.01); A61K 31/397 (2013.01); A61K 31/4164 (2013.01); A61K 31/427 (2013.01); A61K 31/4409 (2013.01); A61K 31/495 (2013.01); A61K 31/519 (2013.01); A61K 31/64 (2013.01); A61K 45/06 (2013.01);
Abstract

The invention provides methods of preventing, treating or ameliorating autoimmune diseases, such as diabetes and celiac disease, by decreasing the binding of MHC class II molecules to antigenic peptides or fragments of antigenic peptides of the autoimmune disease by the administration of small organic compounds. The invention also provides pharmaceutical compositions comprising the therapeutically effective small organic compounds and methods of using the same.


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