The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2017

Filed:

Jun. 05, 2015
Applicants:

The Regents of the University of California, Oakland, CA (US);

Intellikine, Inc., La Jolla, CA (US);

Inventors:

Kevan M. Shokat, San Francisco, CA (US);

David Fruman, Irvine, CA (US);

Pingda Ren, San Diego, CA (US);

Troy Edward Wilson, San Marino, CA (US);

Liansheng Li, San Diego, CA (US);

Andrew Hsieh, San Francisco, CA (US);

Morris Feldman, San Francisco, CA (US);

Beth Apsel, San Francisco, CA (US);

Yi Liu, San Diego, CA (US);

Christian Rommel, La Jolla, CA (US);

Katrina Chan, San Diego, CA (US);

Davide Ruggero, San Francisco, CA (US);

David Pearce, San Francisco, CA (US);

Matthew Janes, Altadena, CA (US);

Assignees:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);

INTELLIKINE, INC., La Jolla, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C12Q 1/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); C12Q 1/485 (2013.01); G01N 2500/04 (2013.01); G01N 2510/00 (2013.01);
Abstract

The present invention provides methods and compositions for selective modulation of certain protein kinases, and especially mTor complexes. The methods and compositions are particularly useful in inhibiting mTor selectively for therapeutic applications.


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