The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2017
Filed:
Oct. 16, 2003
Applicants:
Homme W. Hellinga, Durham, NC (US);
Loren L. Looger, Madison, AL (US);
Inventors:
Homme W. Hellinga, Durham, NC (US);
Loren L. Looger, Madison, AL (US);
Assignee:
Duke University, Durham, NC (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/54 (2006.01); C12M 1/00 (2006.01); G01N 33/566 (2006.01); C12Q 1/00 (2006.01); G01N 33/542 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 33/566 (2013.01); C12Q 1/001 (2013.01); G01N 33/542 (2013.01); G01N 33/54373 (2013.01); G01N 2333/195 (2013.01);
Abstract
Biosensors are made by attaching covalently or non-covalently at least one reporter group to one or more specific positions of a bacterial periplasmic binding protein (bPBP). Upon binding of ligand to the biosensor, there is a change in the signal transduced by the reporter group.