The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2017
Filed:
Mar. 20, 2014
Sanofi Pasteur Vaxdesign Corporation, Orlando, FL (US);
William L Warren, Orlando, FL (US);
Heather Fahlenkamp, Cleveland, OK (US);
Russell Higbee, Orlando, FL (US);
Anatoly Kachurin, Orlando, FL (US);
Conan Li, Los Altos, CA (US);
Mike Nguyen, Orlando, FL (US);
Robert Parkhill, Orlando, FL (US);
Guzman Sanchez-Schmitz, Orlando, FL (US);
Darrell J. Irvine, Arlington, MA (US);
Gwendalyn J. Randolph, New York, NY (US);
Nir Hacohen, Brookline, MA (US);
Bruce Torbett, Encinitas, CA (US);
SANOFI PASTEUR VAXDESIGN CORPORATION, Orlando, FL (US);
THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);
MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Cambridge, MA (US);
THE WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH, Cambridge, MA (US);
MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY, New York, NY (US);
Abstract
The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interaction with the immune system.