The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2017
Filed:
Jul. 29, 2011
Applicants:
Igor I. Slukvin, Verona, WI (US);
Maksym A. Vodyanyk, Madison, WI (US);
James A. Thomson, Madison, WI (US);
Inventors:
Igor I. Slukvin, Verona, WI (US);
Maksym A. Vodyanyk, Madison, WI (US);
James A. Thomson, Madison, WI (US);
Assignee:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0789 (2010.01); C12N 5/071 (2010.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0647 (2013.01); C12N 2502/1394 (2013.01); C12N 2506/02 (2013.01);
Abstract
This invention relates to hematopoietic precursors derived from human embryonic stem cells. In the culture of differentiated cells from human ES cells, the fully committed hematopoietic precursors are CD34+ and CD43+ but not CD45+. If the cells are cultured until they express CD45, then the cells lose the ability to produce differentiated cells of the lymphoid lineages.