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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9624298 B1

PDFFull Text
Date of Patent:
Apr. 18, 2017

Filed:

Nov. 21, 2012

Anti-pd-l1 antibodies and uses thereof

Applicant:

Merck Patent Gmbh, Darmstadt, DE;

Inventors:

Horacio G. Nastri, Needham, MA (US);

Christel Iffland, Cambridge, MA (US);

Olivier Leger, Saint-Sixt, FR;

Qi An, Nashua, NH (US);

Mark Cartwright, West Newton, MA (US);

Sean D. McKenna, Duxbury, MA (US);

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:

Goodwin Procter LLP

Primary Examiner:

Ilia Ouspenski

Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 31/282 (2006.01); A61K 31/675 (2006.01); A61K 31/7068 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01); A61K 31/555 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 31/282 (2013.01); A61K 31/513 (2013.01); A61K 31/519 (2013.01); A61K 31/555 (2013.01); A61K 31/675 (2013.01); A61K 31/7068 (2013.01); A61K 39/0011 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); A61K 39/39591 (2013.01); A61K 45/06 (2013.01); C07K 16/2827 (2013.01); A61K 2039/505 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present application relates to anti-PD-L1 antibodies or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions thereof, and their use to enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, such as tumor immunity, for the treatment of and cancer.

Find Patent Forward Citations

Nastri, Horacio. (2017). Anti-pd-l1 antibodies and uses thereof (U.S. Patent No. 9624298). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9624298

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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