The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2017
Filed:
Apr. 16, 2015
Applicant:
The California Institute for Biomedical Research, La Jolla, CA (US);
Inventors:
Travis Young, La Jolla, CA (US);
Chanhyuk Kim, San Diego, CA (US);
Peter G. Schultz, La Jolla, CA (US);
Assignee:
The California Institute for Biomedical Research, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/395 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); A61K 39/00 (2006.01); C12N 5/10 (2006.01); C07K 19/00 (2006.01); C12N 5/0783 (2010.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/395 (2013.01); C12N 5/0636 (2013.01); A61K 38/00 (2013.01); C07K 2319/01 (2013.01); C07K 2319/30 (2013.01);
Abstract
Disclosed herein are chimeric antigen receptor effector cells (CAR-ECs) and CAR-EC switches. The switchable CAR-ECs are generally T cells. The one or more chimeric antigen receptors may recognize a peptidic antigen on the CAR-EC switch. The CAR-ECs and switches may be used for the treatment of a condition in a subject in need thereof.