The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2017
Filed:
Dec. 14, 2015
Applicant:
Sanofi, Paris, FR;
Inventors:
Assignee:
SANOFI, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/277 (2006.01); A61K 31/216 (2006.01); A61K 31/196 (2006.01); A61K 31/165 (2006.01); A61K 31/5375 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); C07C 217/84 (2006.01); C07C 235/56 (2006.01); C07C 233/75 (2006.01); C07C 255/59 (2006.01); C07C 237/30 (2006.01); C07C 215/76 (2006.01); C07C 65/105 (2006.01); C07C 65/24 (2006.01); C07C 63/72 (2006.01); C07C 213/02 (2006.01); C07C 213/08 (2006.01); C07C 235/20 (2006.01); C07C 253/30 (2006.01); C07C 255/57 (2006.01); C07C 255/58 (2006.01); C07D 295/088 (2006.01);
U.S. Cl.
CPC ...
C07C 217/84 (2013.01); A61K 9/0014 (2013.01); A61K 9/0048 (2013.01); A61K 31/165 (2013.01); A61K 31/196 (2013.01); A61K 31/216 (2013.01); A61K 31/277 (2013.01); A61K 31/5375 (2013.01); A61K 45/06 (2013.01); C07C 63/72 (2013.01); C07C 65/105 (2013.01); C07C 65/24 (2013.01); C07C 213/02 (2013.01); C07C 213/08 (2013.01); C07C 215/76 (2013.01); C07C 233/75 (2013.01); C07C 235/20 (2013.01); C07C 235/56 (2013.01); C07C 237/30 (2013.01); C07C 253/30 (2013.01); C07C 255/57 (2013.01); C07C 255/58 (2013.01); C07C 255/59 (2013.01); C07D 295/088 (2013.01);
Abstract
The present invention relates to therapeutic applications of aniline derivatives of formula (I), for example in treating glaucoma: Formula (I), R1a represents H, an halogen, a (C-C)alkyl or a CN; R1b represents H, an halogen or a (C-C)alkyl; R1c represents H or a (C-C)alkyl; R2 represents H, an halogen, an OH, an O—(C-C)alkyl or (C-C)alkyl; R3 represents H, an halogen, a (C-C)alkyl, an OH, an O—(C-C)alkyl, a CONHor CN; R4 represents H, an halogen or a (C-C)alkyl; R5 represents H or F: R7 represents H or F; R8 represents H or F; R9 represents H or (C-C)alkyl, or one of its enantiomers.