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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9623144 B1

PDFFull Text
Date of Patent:
Apr. 18, 2017

Filed:

May. 27, 2015

Biocompatible hydrogel treatments for retinal detachment

Applicant:

Medicus Biosciences Llc, San Jose, CA (US);

Inventors:

Syed H. Askari, San Jose, CA (US);

Yeon S. Choi, Emeryville, CA (US);

Assignee:

MEDICUS BIOSCIENCES LLC, San Jose, CA (US);

Attorney:

Pepper Hamilton LLP

Primary Examiner:

James Rogers

Int. Cl.
CPC ...
A61K 8/00 (2006.01); A61L 26/00 (2006.01); A61K 9/00 (2006.01); A61K 47/18 (2017.01); A61K 47/20 (2006.01); A61K 47/32 (2006.01); A61K 47/38 (2006.01); A61K 9/70 (2006.01); A61L 27/18 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); A61L 24/00 (2006.01); A61L 24/04 (2006.01); A61L 27/58 (2006.01); A61K 51/12 (2006.01); A61F 9/007 (2006.01);
U.S. Cl.
CPC ...
A61L 26/0019 (2013.01); A61K 9/0051 (2013.01); A61K 9/7015 (2013.01); A61K 47/18 (2013.01); A61K 47/20 (2013.01); A61K 47/32 (2013.01); A61K 47/38 (2013.01); A61L 24/0031 (2013.01); A61L 24/0042 (2013.01); A61L 24/046 (2013.01); A61L 26/008 (2013.01); A61L 26/009 (2013.01); A61L 26/0023 (2013.01); A61L 26/0066 (2013.01); A61L 27/18 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); A61F 9/007 (2013.01); A61F 9/00727 (2013.01); A61K 51/1213 (2013.01); A61L 2300/402 (2013.01); A61L 2300/406 (2013.01); A61L 2300/41 (2013.01); A61L 2300/416 (2013.01); A61L 2300/418 (2013.01); A61L 2400/06 (2013.01); A61L 2430/16 (2013.01); C08J 2300/206 (2013.01);
Abstract

Provided herein are in vivo gelling ophthalmic pre-formulations forming a biocompatible retinal patch comprising at least one nucleophilic compound or monomer unit, at least one electrophilic compound or monomer unit, and optionally a therapeutic agent and/or viscosity enhancer. In some embodiments, the retinal patch at least partially adheres to the site of a retinal tear. Also provided herein are methods of treating retinal detachment by delivering an in vivo gelling ophthalmic pre-formulation to the site of a retinal tear in human eye, wherein the in vivo gelling ophthalmic pre-formulation forms a retinal patch.

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