The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2017

Filed:

Sep. 03, 2013
Applicants:

Shimadzu Corporation, Kyoto-shi, Kyoto, JP;

Kyoto University, Kyoto-shi, Kyoto, JP;

Inventors:

Isao Hara, Kyoto, JP;

Eiichi Ozeki, Kyoto, JP;

Shunsaku Kimura, Kyoto, JP;

Akira Makino, Kyoto, JP;

Assignees:

SHIMADZU CORPORATION, Kyoto, JP;

KYOTO UNIVERSITY, Kyoto, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/74 (2006.01); A61K 49/00 (2006.01); A61K 9/51 (2006.01); A61K 47/48 (2006.01); A61K 51/04 (2006.01); A61K 49/12 (2006.01); A61K 51/06 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0054 (2013.01); A61K 9/5153 (2013.01); A61K 47/482 (2013.01); A61K 49/0034 (2013.01); A61K 49/0089 (2013.01); A61K 47/48 (2013.01); A61K 47/48007 (2013.01); A61K 49/12 (2013.01); A61K 49/124 (2013.01); A61K 51/0404 (2013.01); A61K 51/06 (2013.01);
Abstract

The present invention provides a molecular assembly whose retention time in a target site is adjusted depending on the kind or purpose of a labeling agent or drug encapsulated therein, and a molecular assembly that can suppress the ABC phenomenon and that can be administered more than once within a short span. A molecular assembly comprising: a branched-type amphiphilic block polymer A comprising a branched hydrophilic block comprising sarcosine and a hydrophobic block comprising a polylactic acid chain; and a functional substance F comprising a functional site and a polylactic acid chain, wherein the polylactic acid chain constituting the hydrophobic block of the amphiphilic block polymer A comprises L-lactic acid units, and the polylactic acid chain contained in the functional substance F comprises D-lactic acid units, or the polylactic acid chain constituting the hydrophobic block of the amphiphilic block polymer A comprises D-lactic acid units, and the polylactic acid chain contained in the functional substance F comprises L-lactic acid units.


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