The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2017

Filed:

Apr. 12, 2013
Applicants:

Institute of Pharmacology and Toxicology Academy of Military Medical Sciences Pla China, Beijing, CN;

Kpc Pharmaceuticals, Inc., Kunming, Yunnan Province, CN;

Inventors:

Sicheng Li, Beijing, CN;

Qingbin Meng, Beijing, CN;

Junwen Mao, Beijing, CN;

Jinfeng Li, Beijing, CN;

An Xu, Beijing, CN;

Jia Liu, Beijing, CN;

Yuanjun Liang, Beijing, CN;

Qiyan Jia, Beijing, CN;

Jiufeng Yan, Beijing, CN;

Xiaoyang Shen, Beijing, CN;

Hui Liu, Beijing, CN;

Na Xing, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/335 (2006.01); A61K 31/35 (2006.01); C07D 323/00 (2006.01); A61K 31/765 (2006.01); A61K 47/48 (2006.01); C08G 65/332 (2006.01); A61K 31/357 (2006.01); C08G 65/333 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48215 (2013.01); A61K 31/357 (2013.01); A61K 31/765 (2013.01); A61K 47/481 (2013.01); C08G 65/332 (2013.01); C08G 65/33396 (2013.01); C08L 2203/02 (2013.01);
Abstract

A pegylated artesunate derivative, a pharmaceutical composition and uses thereof, the pegylated artesunate derivative is represented by the general formula (I): The pegylated artesunate derivative has activity comparable to that of artesunate, increased water solubility and stability, and an extended half-life in vivo.


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