The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2017
Filed:
Dec. 21, 2015
Applicant:
Merial Inc., Duluth, GA (US);
Inventor:
Benjamin M. Hause, Currie, MN (US);
Assignee:
MERIAL, INC., Duluth, GA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); A61K 39/02 (2006.01); A61K 39/21 (2006.01); A61K 39/12 (2006.01); C12N 7/04 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61K 39/0241 (2013.01); A61K 39/12 (2013.01); A61K 39/21 (2013.01); C12N 7/00 (2013.01); C12N 7/04 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/552 (2013.01); C12N 2760/16121 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16161 (2013.01);
Abstract
This disclosure provides attenuated swine influenza strains, particularly those produced via a reverse genetics approach, compositions comprising same, and methods of production and use thereof. The attenuated strains are engineered to encode HA proteins having additional glycosylation sites, relative to the HA proteins encoded by the corresponding virulent parental viruses. Advantageously, the attenuated influenza strains may be administered.