The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2017
Filed:
Jul. 28, 2015
Wyeth Llc, New York, NY (US);
Stephen John Freese, Cornwall-on-Hudson, NY (US);
Annaliesa Anderson, Upper Saddle River, NJ (US);
Viliam Pavliak, Montebello, NY (US);
Kathrin Ute Jansen, New York, NY (US);
Ingrid Lea Scully, Cornwall, NY (US);
Tracy Dee Scott, Foristell, MO (US);
Jasdeep Singh Nanra, Suffren, NY (US);
A. Krishna Prasad, Chapel Hill, NC (US);
Bruce Arthur Green, New City, NY (US);
Wyeth LLC, New York, NY (US);
Abstract
The present invention relates to immunogenic conjugates comprisingserotype 5 and 8 capsular polysaccharides conjugated to carrier proteins and methods for their preparation and use. Methods for making the immunogenic conjugates of the invention involve covalent conjugation of the capsular polysaccharides with the carrier proteins using conjugation chemistry involving either 1,1-carbonyl-di-1,2,4-triazole (CDT) or 3-(2-pyridyldithio)-propionyl hydrazide (PDPH).