The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2017
Filed:
Jul. 16, 2013
Universite Claude Bernard Lyon I, Villeurbanne, FR;
Institut National Des Sciences Appliquees DE Lyon, Villeurbanne, FR;
Universite Jean Monnet, Saint Etienne, Saint Etienne, FR;
Centre National DE LA Recherche Scientifique, Paris, FR;
Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;
Universite Pierre ET Marie Curie (Paris 6), Paris, FR;
Fatiha Nothias, Paris, FR;
Sylvia Soares, Les Lilas, FR;
Laurent David, Lyons, FR;
Alexandra Montembault, Saint Etienne, FR;
UNIVERSITE CLAUDE BERNARD LYON I, Villeurbanne, FR;
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, Villeurbanne, FR;
UNIVERSITE JEAN MONNET, SAINT ETIENNE, Saint Etienne, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), Paris, FR;
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), Paris, FR;
Abstract
The present invention relates to chitosan hydrogel microparticles of a median size d50 comprised between 1 and 500 μm (obtained from a number distribution), the chitosan having a degree of acetylation of less than equal to 20% and its concentration in the hydrogel being comprised between 0.25 and 5% by weight based on a total weight of the hydrogel, for use in neuron regeneration and/or in the repair of the nervous system, advantageously of the central nervous system, and/or in the grafting of neurons and/or in the treatment of neurodegenerative diseases and/or in the treatment of paralyses. It also relates to an implant comprising an aqueous suspension of microparticles mixed with Schwann cells and/or stem cells and/or trophic factors.