The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2017

Filed:

Nov. 11, 2011
Applicants:

Ted M. Dawson, Baltimore, MD (US);

Valina L. Dawson, Baltimore, MD (US);

Shaida A. Andrabi, Baltimore, MD (US);

Ho Chul Kang, Parkville, MD (US);

Inventors:

Ted M. Dawson, Baltimore, MD (US);

Valina L. Dawson, Baltimore, MD (US);

Shaida A. Andrabi, Baltimore, MD (US);

Ho Chul Kang, Parkville, MD (US);

Assignee:

VALTED, LLC, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/7088 (2006.01); A61K 31/7105 (2006.01); C12N 9/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/7088 (2013.01); A61K 31/7105 (2013.01); C12N 9/93 (2013.01); A61K 48/005 (2013.01); C12N 15/1137 (2013.01); C12N 2310/14 (2013.01); C12Y 603/02019 (2013.01);
Abstract

Research into neuroprotective mechanisms has at its heart the goal of developing new therapeutic strategies to treat patients. For example, the compositions and induction strategies disclosed herein have use for acute injuries such as stroke or trauma, and would be extremely useful in treating patients undergoing cardiac bypass surgery, neurosurgery or other surgical cohorts where ischemia is a risk. Further, patients with subarachnoid hemorrhage, transient ischemic attacks, soldiers at risk for blast injury or patients suffering from chronic neurodegenerative diseases would also benefit from enhanced neuronal survival based upon the techniques and compositions disclosed herein. In addition, protecting against cell death by, for example, interfering with PAR polymer signaling via the compositions and processes disclosed herein, offers new therapeutic strategies for the treatment of neurologic disorders.


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