The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2017
Filed:
Jun. 04, 2014
Applicant:
The University of Chicago, Chicago, IL (US);
Inventors:
Deng Pan, Chicago, IL (US);
Masha Kocherginsky, Chicago, IL (US);
Suzanne D. Conzen, Park Ridge, IL (US);
Assignee:
THE UNIVERSITY OF CHICAGO, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C12Q 1/68 (2006.01); A61K 31/567 (2006.01); A61K 31/575 (2006.01); A61K 45/06 (2006.01); A61K 31/282 (2006.01); A61K 31/337 (2006.01); A61K 31/357 (2006.01); A61K 31/4745 (2006.01); A61K 31/7068 (2006.01); A61K 33/24 (2006.01); A61K 39/395 (2006.01); A61N 5/00 (2006.01); A61J 1/00 (2006.01); A61K 31/58 (2006.01);
U.S. Cl.
CPC ...
A61K 31/567 (2013.01); A61J 1/00 (2013.01); A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/357 (2013.01); A61K 31/4745 (2013.01); A61K 31/575 (2013.01); A61K 31/58 (2013.01); A61K 31/7068 (2013.01); A61K 33/24 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61N 5/00 (2013.01);
Abstract
Embodiments of the invention are directed to methods of determining the prognosis of a breast cancer patient by evaluating the activity of the glucocorticoid receptor in tumor cells. Other embodiment include methods of treating breast cancer cells, particularly, chemo-resistant cells, with a glucocorticoid receptor antagonist and an anticancer agent or compound.