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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9623018 B1

PDFFull Text
Date of Patent:
Apr. 18, 2017

Filed:

Jun. 07, 2016

Processes of making and crystalline forms of a mdm2 inhibitor

Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Matthew Bio, Belmont, MA (US);

Sebastien Caille, Moorpark, CA (US);

Yuanqing Fang, Belmont, MA (US);

Brian M. Fox, Brisbane, CA (US);

Brian S. Lucas, Arlington, MA (US);

Lawrence R. McGee, Pacifica, CA (US);

Sean H. Wiedemann, Cambridge, MA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:

Markus Bergauer

Primary Examiner:

David K O'Dell

Int. Cl.
CPC ...
C07D 498/04 (2006.01); A61K 31/451 (2006.01); C07D 211/94 (2006.01); C07D 491/048 (2006.01); C07C 309/25 (2006.01); C07C 309/04 (2006.01); C07D 211/76 (2006.01); C07C 309/35 (2006.01);
U.S. Cl.
CPC ...
A61K 31/451 (2013.01); C07C 309/04 (2013.01); C07C 309/25 (2013.01); C07C 309/35 (2013.01); C07D 211/76 (2013.01); C07D 211/94 (2013.01); C07D 491/048 (2013.01); C07D 498/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates and processes for making the intermediates. Also provided are crystalline forms of the compound and the intermediates.

Find Patent Forward Citations

Bio, Matthew. (2017). Processes of making and crystalline forms of a mdm2 inhibitor (U.S. Patent No. 9623018). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9623018

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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