The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2017

Filed:

Apr. 08, 2014
Applicant:

South Dakota State University, Brookings, SD (US);

Inventors:

Omathanu P. Perumal, Brookings, SD (US);

Satheesh K. Podaralla, Creve Coeur, MO (US);

Ranjith Kumar Averineni, Portage, MI (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/107 (2006.01); A61K 31/12 (2006.01); A61K 31/704 (2006.01); A61K 31/07 (2006.01); A61K 31/337 (2006.01); B82Y 5/00 (2011.01); C07K 14/415 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 9/12 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 8/64 (2006.01); A61K 8/67 (2006.01); A61Q 19/00 (2006.01); A61K 8/86 (2006.01); A61K 8/11 (2006.01); A61K 47/10 (2017.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
A61K 9/1075 (2013.01); A61K 8/11 (2013.01); A61K 8/64 (2013.01); A61K 8/671 (2013.01); A61K 8/86 (2013.01); A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 9/06 (2013.01); A61K 9/12 (2013.01); A61K 9/2031 (2013.01); A61K 9/2063 (2013.01); A61K 9/4808 (2013.01); A61K 31/07 (2013.01); A61K 31/12 (2013.01); A61K 31/337 (2013.01); A61K 31/704 (2013.01); A61Q 19/00 (2013.01); B82Y 5/00 (2013.01); C07K 14/415 (2013.01); A61K 47/10 (2013.01); A61K 47/42 (2013.01); A61K 2800/412 (2013.01);
Abstract

The invention encompasses micelle assemblies, compositions having micelle assemblies, and methods for preparing micelle assemblies and compositions thereof. The invention also encompasses a prolamine protein conjugated to a polymer, such as a polyethylene glycol (PEG) chain, which conjugates can be used to prepare micelle assemblies. The invention further encompasses methods of encapsulating molecules using the conjugates of the invention. The micelle assemblies can be used for a variety of applications, such as treating cancer, targeting tumors, reducing the toxicity of a drug in vivo, increasing the efficacy of an encapsulated agent in vivo, protecting an encapsulated agent against degradation, and enhancing the water solubility of a drug or other agent.


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