The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2017

Filed:

Jan. 08, 2014
Applicant:

Enzo Biochem, Inc., New York, NY (US);

Inventors:

Gerard Nuovo, Westerville, OH (US);

Virginia Nivar, Marion, OH (US);

Assignee:

Enzo Biochem, Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); C12Q 1/68 (2006.01); G01N 33/569 (2006.01); C07K 16/08 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/705 (2013.01); C07K 16/085 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/6886 (2013.01); G01N 33/56994 (2013.01); C07K 2317/76 (2013.01); C12N 2710/16021 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/03 (2013.01); G01N 2800/7052 (2013.01);
Abstract

Provided are methods of diagnosing a viral disease such as idiopathic pulmonary fibrosis, Castleman's disease, a lymphoma, a thymoma or a sarcoma in a patient by identifying one or more virus-specific elements such as a nucleic acid or a viral protein or a patient antibody to a virus-specific element, as well as to kits for diagnosing the viral disease in a patient. Further provided are methods of monitoring disease progression and/or the efficacy of therapy by measuring the levels of a virus-specific element in a sample from a patient, and methods of identifying therapeutic agents that show efficacy in reducing levels of virus-specific agents in vitro. Still further provided are methods of treating idiopathic pulmonary fibrosis, a lymphoproliferative disease and cancer, as well as methods of preventing viral infection, including Herpesvirus saimiri infection.


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