The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Jun. 25, 2013
Applicants:
Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);
Baylor College of Medicine, Houston, TX (US);
Inventors:
Frank Rigo, Carlsbad, CA (US);
Amanda Ward, Carlsbad, CA (US);
Linyan Meng, Houston, TX (US);
Arthur L. Beaudet, Houston, TX (US);
Assignees:
Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);
Baylor College of Medicine, Houston, TX (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 2310/11 (2013.01); C12N 2310/111 (2013.01); C12N 2310/113 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/323 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/341 (2013.01); C12N 2320/30 (2013.01);
Abstract
Certain embodiments are directed to methods and compounds for inhibiting UBE3A-ATS, the endogenous antisense transcript of ubiquitin protein ligase E3A (UBE3A). Such methods and compounds are useful for inducing expression of paternal UBE3A in cells and animals.