The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Aug. 13, 2014
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
David R. Tabatadze, Worcester, MA (US);
Paul C. Zamecnik, Boston, MA (US);
Malay K. Raychowdhury, Lexington, MA (US);
Horacio F. Cantiello, Rowley, MA (US);
Assignee:
THE GENERAL HOSPITAL CORPORATION, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/10 (2006.01); C12N 15/113 (2010.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/102 (2013.01); C12N 15/1024 (2013.01); C12N 15/113 (2013.01); A61K 48/00 (2013.01); C07K 2319/07 (2013.01); C07K 2319/10 (2013.01); C12N 2310/11 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/346 (2013.01); C12N 2310/3519 (2013.01); C12N 2320/30 (2013.01);
Abstract
Compositions and methods of treatments of cells are provided for altering the phenotype of a cell by administering an oligonucleotide complex to the cell, the complex having two strands and chemical modifications.