The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Mar. 17, 2014
Vib Vzw, Ghent, BE;
Vrije Universiteit Brussel, Brussels, BE;
Patrick De Baetselier, Berchem, BE;
Geert Raes, Sint-Genesius-Rode, BE;
Steve Schoonooghe, Kessel-Lo, BE;
Jens De Vos, Grimbergen, BE;
Tony Lahoutte, Ganshoren, BE;
Nick Devoogdt, Zemst, BE;
Sophie Hernot, Machelen, BE;
Gezim Bala, Brussels, BE;
Simon Tierens, Londerzeel, BE;
VIB VZW, Ghent, BE;
Vrije Universiteit Brussel, Brussels, BE;
Abstract
The disclosure relates to the field of cardiovascular diseases. In particular, immunoglobulin single variable domains directed against macrophage mannose receptor (MMR) are provided that can be used in the diagnosis, prognosis and/or monitoring of cardiovascular diseases or as therapeutics. Also, the anti-macrophage mannose receptor (MMR) immunoglobulin single variable domains of the disclosure are useful at different stages of cardiovascular diseases, including post-infarction cardiovascular events. Further, the anti-macrophage mannose receptor (MMR) immunoglobulin single variable domains of the disclosure are particularly useful for the in vivo targeting and/or imaging of vulnerable atherosclerotic plaques.