The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Dec. 29, 2014
Applicants:
Boston Medical Center Corporation, Boston, MA (US);
Trustees of Boston University, Boston, MA (US);
Inventors:
Lisa Ganley-Leal, Newton, MA (US);
John H. Connor, Newton, MA (US);
Assignees:
Boston Medical Center Corporation, Boston, MA (US);
Trustees of Boston University, Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); C07K 14/435 (2006.01); C07K 14/705 (2006.01); A61K 31/56 (2006.01); A61K 45/06 (2006.01); C07K 14/195 (2006.01); A61K 39/00 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7056 (2013.01); A61K 31/56 (2013.01); A61K 38/17 (2013.01); A61K 39/0005 (2013.01); A61K 45/06 (2013.01); C07K 14/195 (2013.01); A61K 38/00 (2013.01);
Abstract
The methods and compositions described herein are based, in part, on the discovery of a polypeptide of soluble CD23 (sCD23) that binds and sequesters IgE. Thus, the sCD23 peptides, polypeptides and derivatives described herein are useful for treating conditions or disorders involving increased IgE levels such as e.g., allergy, anaphylaxis, inflammation, lymphoma, and certain cancers.