The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2017

Filed:

Aug. 14, 2013
Applicants:

Mark F. Leppert, Salt Lake City, UT (US);

Nanda A. Singh, Heber City, UT (US);

Inventors:

Mark F. Leppert, Salt Lake City, UT (US);

Nanda A. Singh, Heber City, UT (US);

Assignee:

University of Utah Research Foundation, Salt Lake City, UT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C07K 14/47 (2006.01); C12N 15/85 (2006.01); C07K 14/705 (2006.01); C12Q 1/68 (2006.01); A01K 67/027 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); A01K 67/0275 (2013.01); C07K 14/705 (2013.01); C12N 15/85 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/172 (2013.01);
Abstract

Described are mutant Na1.7 sodium channel alpha-subunits and nucleic acid sequences encoding such mutants. Further described are methods for characterizing a nucleic acid sequence that encodes a Na1.7 sodium channel alpha-subunit, methods for determining a Na1.7 haplotype, methods for determining a subject's predisposition to a neurologic disorder associated with a sodium channel mutation, and methods of identifying a compound that modulates mutant Na1.7 sodium channels. Other materials, compositions, articles, devices, and methods relating to mutant Na1.7 sodium channels are also described herein.


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