The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Mar. 02, 2012
Young Woo Park, Daejeon, KR;
Ki Won JO, Daejeon, KR;
Kyu Won Cho, Daejeon, KR;
Ji Hyun Park, Daejeon, KR;
Soon Sil Hyun, Daejeon, KR;
Yun Jung Park, Daejeon, KR;
Young Woo Park, Daejeon, KR;
Ki Won Jo, Daejeon, KR;
Kyu Won Cho, Daejeon, KR;
Ji Hyun Park, Daejeon, KR;
Soon Sil Hyun, Daejeon, KR;
Yun Jung Park, Daejeon, KR;
Korea Research Institute Of Bioscience And Biotechnology, Daejeon, KR;
Abstract
The present invention relates to a novel endocytic motif, and in particular, to a fusion polypeptide including the motif represented by an amino acid sequence of SEQ ID NO. 1 and a protein transduction domain, a pharmaceutical composition for preventing or treating cancer including the same, and a method for treating cancer including the step of administering the composition. The present invention shows the effects of suppressing metastasis, infiltration, angiogenesis, and growth of cancer by specifically inhibiting c-Met endocytosis and effectively inhibiting HGF/c-Met signaling pathway associated with metastasis and growth of various types of cancer cells. Therefore, the present invention can be applied to an anticancer agent for various types of cancer.