The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9617280 B1

PDF
Full Text
Expired
Date of Patent:
Apr. 11, 2017

Filed:

May. 15, 2014
Applicant:

Council of Scientific & Industrial Research, New Delhi, IN;

Inventors:

Biju Akkattu Thankappan, Maharashtra, IN;

Anup Bhunia, Maharashtra, IN;

Tony Roy, Maharashtra, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/20 (2006.01); C07D 498/22 (2006.01); C07D 401/04 (2006.01); C07D 498/10 (2006.01);
U.S. Cl.
CPC ...
C07D 498/22 (2013.01); C07D 401/04 (2013.01); C07D 498/10 (2013.01); C07D 498/20 (2013.01);
Abstract

The present invention relates to novel spiro-oxazine analogues of Formula-I and Indolinone compounds of Formula-II or positional isomers, or stereoisomers, or derivatives, or pharmaceutically acceptable salt thereof. Formula-I Formula-II Further the invention provides transition-metal free multicomponent reaction (MCR) process for the preparation of said compounds of Formula-I and II using aryne precursor, N-substituted isatin and N-heteroaromatic compound as the nucleophile, under mild condition leading to formation of desired complex of spiro-oxazine analogues (I) and indolinone analogues (II) in high yield and selectivity.


Find Patent Forward Citations

Thankappan, Biju. (2017). Spiro-oxazines, indolinones and preparation thereof (U.S. Patent No. 9617280). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9617280

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