The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2017

Filed:

Apr. 07, 2016
Applicant:

Roche Palo Alto Llc, South San Francisco, CA (US);

Inventors:

Li Chen, Shanghai, CN;

Michael Patrick Dillon, San Francisco, CA (US);

Lichun Feng, Shanghai, CN;

Ronald Charles Hawley, Mountain View, CA (US);

Minmin Yang, Shanghai, CN;

Assignee:

Roche Palo Alto LLC, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 61/00 (2006.01); A61K 31/00 (2006.01); C07D 417/14 (2006.01); C07D 261/08 (2006.01); C07D 263/32 (2006.01); C07D 275/02 (2006.01); C07D 277/30 (2006.01); C07D 277/66 (2006.01); C07D 417/12 (2006.01); C07D 277/56 (2006.01); C07D 413/14 (2006.01); C07D 417/10 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 261/08 (2013.01); C07D 263/32 (2013.01); C07D 275/02 (2013.01); C07D 277/30 (2013.01); C07D 277/56 (2013.01); C07D 277/66 (2013.01); C07D 413/14 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01);
Abstract

Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, Ris a group of formula A or formula B, and X, R, R, R, R, R, Rand Rare as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2Xand/or a P2Xreceptor antagonist and methods of making the subject compounds.


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