The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2017

Filed:

Dec. 21, 2015
Applicant:

Farmington Pharma Development, Cheshire, CT (US);

Inventor:

William F. Brubaker, Cheshire, CT (US);

Assignee:

FARMINGTON PHARMA DEVELOPMENT, Cheshire, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 273/06 (2006.01); C07D 279/14 (2006.01); C07D 271/07 (2006.01); C07D 273/04 (2006.01); C07C 279/14 (2006.01);
U.S. Cl.
CPC ...
C07D 273/06 (2013.01); C07C 279/14 (2013.01); C07D 271/07 (2013.01); C07D 273/04 (2013.01);
Abstract

The invention describes membrane permeable creatine prodrugs, pharmaceutical compositions comprising membrane permeable creatine prodrugs, and methods of treating diseases such as ischemia, heart failure, neurodegenerative disorders and genetic disorders affecting the creatine kinase system comprising administering creatine prodrugs or pharmaceutical compositions thereof. The invention also describes treating a genetic disease affecting the creatine kinase system, such as, for example, a creatine transporter disorder or a creatine synthesis disorder comprising administering creatine prodrugs or pharmaceutical compositions thereof.


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