The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Jun. 10, 2014
Applicant:
Scinopharm (Changshu) Pharmaceuticals, Ltd., Changshu, Jiangsu Province, CN;
Inventors:
Xiaoheng Zhang, Changshu, CN;
Xizhou Lv, Changshu, CN;
Assignee:
SCINOPHARM (CHANGSHU) PHARMACEUTICALS, LTD., Changshu, CN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/94 (2006.01);
U.S. Cl.
CPC ...
C07D 239/94 (2013.01);
Abstract
A concise, efficient and cost- and time-saving process for the preparation of a quinazoline derivative of formula A given below: which is an intermediate for making gefitinib or gefitinib itself, comprising reacting a compound of Formula B: with 3-chloro-4-fluoroaniline (VI) in the presence of a N,N-dialkyl formamide acetal, a Bronsted acid catalyst, and a solvent in a one-pot reaction.