The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Nov. 10, 2014
Applicants:
The Translational Genomics Research Institute, Phoenix, AZ (US);
Translational Drug Development, Llc, Scottsdale, AZ (US);
Inventors:
Tong Wang, Phoenix, AZ (US);
Travis Dunckley, Phoenix, AZ (US);
Matthew Huentelman, Phoenix, AZ (US);
Assignee:
The Translational Genomics Research Institute, Phoenix, AZ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); C07D 213/56 (2006.01); C07D 405/12 (2006.01); A61K 31/4409 (2006.01); A61K 31/4433 (2006.01); A61K 31/4418 (2006.01);
U.S. Cl.
CPC ...
C07D 213/56 (2013.01); A61K 31/4409 (2013.01); A61K 31/4418 (2013.01); A61K 31/4433 (2013.01); A61K 45/06 (2013.01); C07D 405/12 (2013.01);
Abstract
The invention provides compounds that inhibit ROCK activity. In certain embodiments the compounds of the invention enhance cognitive function. The invention is also directed to pharmaceutical compositions that comprise ROCK inhibitors and to methods enhance cognitive function and reducing and/or treat cognitive function decline.