The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Oct. 19, 2009
Applicants:
Rajiv Bhushan, Palo Alto, CA (US);
Jerry B. Gin, Sunnyvale, CA (US);
Amit Goswamy, Los Gatos, CA (US);
Inventors:
Rajiv Bhushan, Palo Alto, CA (US);
Jerry B. Gin, Sunnyvale, CA (US);
Amit Goswamy, Los Gatos, CA (US);
Assignee:
Livionex Inc., Los Gatos, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/10 (2006.01); A61K 31/195 (2006.01); A61K 45/06 (2006.01); A61K 47/20 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/20 (2013.01); A61K 9/0014 (2013.01); A61K 31/10 (2013.01); A61K 31/195 (2013.01); A61K 45/06 (2013.01);
Abstract
Methods and formulations are provided for the treatment of localized edema, particularly localized edema resulting from chronic venous insufficiency. A metal ion sequestrant is topically administered to a subject afflicted with localized edema in combination with a permeation enhancer selected from methylsulfonylmethane and a combination of methylsulfonylmethane and dimethylsulfoxide. Topically administrable formulations for use in the aforementioned method are also provided.