logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9616122 B1

PDFFull Text
Date of Patent:
Apr. 11, 2017

Filed:

Jul. 03, 2009

Ph sensitive metal nanoparticle and preparation method

Applicants:

Sung Jee Kim, Pohang-si, KR;

Sang Hwa Jeong, Pohang-si, KR;

Hyo Kyun Chung, Jung-gu, KR;

Ju Taek Nam, Pohang-si, KR;

NA Youn Won, Pohang-si, KR;

Inventors:

Sung Jee Kim, Pohang-si, KR;

Sang Hwa Jeong, Pohang-si, KR;

Hyo Kyun Chung, Jung-gu, KR;

Ju Taek Nam, Pohang-si, KR;

Na Youn Won, Pohang-si, KR;

Assignee:

POSTECH ACADEMY-INDUSTRY FOUNDATION, Pohang-si, Gyungbuk, KR;

Attorney:

Steptoe & Johnson LLP

Primary Examiner:

Michael G Hartley

Assistant Examiner:

Lance Rider

Int. Cl.
CPC ...
A61K 41/00 (2006.01); A61K 49/00 (2006.01); A61K 51/04 (2006.01); A61K 47/48 (2006.01); A61K 51/12 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 41/0052 (2013.01); A61K 47/4813 (2013.01); A61K 49/0065 (2013.01); A61K 51/0402 (2013.01); A61B 2562/0285 (2013.01); A61K 51/1255 (2013.01); B82Y 5/00 (2013.01);
Abstract

The present invention relates to a pH sensitive particle, a method of preparation thereof, and a use thereof. More particularly, the invention provides a pH sensitive metal nanoparticle and its use for medical treatment utilizing cell necrosis during photothermal therapy. The pH sensitive metal nanoparticle based on this invention consists of a pH sensitive ligand compound whose charge changes depending on the pH of the metal nanoparticle. The particle can be collected in cells, such as cancer cells which present an abnormal pH environment. The pH sensitive metal nanoparticle based on this invention can induce cell death through a photothermal procedure after aggregation. Therefore, the invention enables medical treatment using cell necrosis for e.g. cancer treatment.

Find Patent Forward Citations

Kim, Sung. (2017). Ph sensitive metal nanoparticle and preparation method (U.S. Patent No. 9616122). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9616122

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…