The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2017

Filed:

Mar. 03, 2015
Applicants:

Alan S. Cross, Chevy Chase, MD (US);

Apurba K. Bhattacharjee, Kensington, MD (US);

Wendell D. Zollinger, Leahi, UT (US);

Steven M. Opal, Barrington, RI (US);

Inventors:

Alan S. Cross, Chevy Chase, MD (US);

Apurba K. Bhattacharjee, Kensington, MD (US);

Wendell D. Zollinger, Leahi, UT (US);

Steven M. Opal, Barrington, RI (US);

Assignees:

UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);

THE MEMORIAL HOSPITAL OF RHODE ISLAND, Pawtucket, RI (US);

UNITED STATES ARMY, Fort Detrick, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/095 (2006.01); A61K 39/108 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0258 (2013.01); A61K 39/095 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/55583 (2013.01); A61K 2039/58 (2013.01); A61K 2039/70 (2013.01);
Abstract

The present invention provides an immunogenic composition of a lipopolysaccharide vaccine and a non-alum adjuvant. The immunogenic composition may be detoxified J5 core lipopolysaccharide ofnon-covalently complexed with group B meningococcal outermembrane protein. Also provided are methods for preventing an infection caused by a Gram-negative bacteria in an individual via administering the immunogenic compositions to the individual.


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