The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9616086 B1

PDF
Full Text
Expired
Date of Patent:
Apr. 11, 2017

Filed:

Jan. 26, 2014
Applicant:

Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, CN;

Inventors:

Bin Hong, Beijing, CN;

Li Wang, Beijing, CN;

Xiaojian Jia, Beijing, CN;

Huajun Jiang, Beijing, CN;

Yu Du, Beijing, CN;

Fan Yang, Beijing, CN;

Shuyi Si, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 31/713 (2006.01); C12Q 1/68 (2006.01); A61K 31/7105 (2006.01); C12N 15/113 (2010.01); G01N 33/92 (2006.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 31/7105 (2013.01); C12N 15/113 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/6897 (2013.01); G01N 33/92 (2013.01); C12N 2310/113 (2013.01); C12N 2310/141 (2013.01); C12N 2320/30 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01); G01N 2405/00 (2013.01); G01N 2500/04 (2013.01); G01N 2500/10 (2013.01); G01N 2800/044 (2013.01);
Abstract

The present invention relates to use of a microRNA or an inhibitor thereof, and specifically, the present invention relates to use of a microRNA or an inhibitor thereof in preparing a medicament for regulating lipid metabolism or preparing a medicament for preventing or treating a disease related to lipid metabolism. The microRNA is one or more of the following: miRNA-96, miRNA-185, and miRNA-223. The present invention also relates to use of the microRNA or the inhibitor thereof in regulating the expression level of a protein related to lipid metabolism. The present invention also relates to a composition comprising the microRNA or the inhibitor thereof. The microRNA or the inhibitor thereof in the present invention can be used as a pharmaceutical component, and can be applied in preventing or treating a disease caused by lipid metabolism disorders such as hyperlipidemia, atherosclerosis, coronary heart disease or other diseases.


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