The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Nov. 25, 2015
Astrazeneca Ab, Södertälje, SE;
Tord Bertil Inghardt, Mölndal, SE;
Petra Johannesson, Mölndal, SE;
Ulrik Jurva, Mölndal, SE;
Eva-Lotte Lindstedt-Alstermark, Mölndal, SE;
Nicholas Tomkinson, Macclesfield, GB;
Jeffrey Paul Stonehouse, Waltham, MA (US);
AstraZeneca AB, Sodertalje, SE;
Abstract
There are disclosed certain 1-[2-(aminomethyl)benzyl]-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-one compounds of formula (I), and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme MPO and are thereby particularly useful in the treatment or prophylaxis of cardiovascular disorders such as heart failure and coronary artery disease related conditions.