The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Oct. 29, 2014
Echo Pharmaceuticals B.v., Weesp, NL;
Jan Albert De Vries, Zelhem, NL;
Maria Vanesa Fernandez Cid, Haarlem, NL;
Ana Maria Heredia Lopez, Amsterdam, NL;
Cristina Maria Eiroa Martinez, Amsterdam, NL;
Echo Pharmaceuticals B.V., Weesp, NL;
Abstract
The present invention relates to compressed tablets for peroral delivery of the cannabinoid Δ9-tetrahydrocannabinol(THC). More particularly, the invention provides a compressed tablet having a tablet weight of 25-1000 mg, said tablet being composed of: compressed tablet containing delta 9-tetrahydrocannabinol, method for its manufacture and use of such tablet in oral treatment •30-90 wt % of a granulate; •10-70 wt % of lactose; and •0-30 wt % of other tablet excipients; wherein the granulate contains: a.2-5 wt % of Δ9-tetrahydrocannabinol; b.2-20 wt % of sucrose fatty acid mono-ester; c.50-96 wt % of lactose; d.0.05-0.6 wt % of antioxidant; and e.0-25 wt % of other granulate excipients. The compressed tablets according to the invention can conveniently be used in the treatment of spasticity and pain caused by multiple sclerosis, neurophatic pain, chronic pain, behavioral disturbance by Alzheimer's disease, stroke, spinal cord injury, peripheral neuropathy, neurogenic pain, nociceptive pain and nausea. The invention further provides a method for the manufacture of the compressed tablets.