The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Apr. 01, 2015
Applicant:
Celgene Corporation, Summit, NJ (US);
Inventors:
Ming J. Chen, West Windsor, NJ (US);
Ho-Wah Hui, Basking Ridge, NJ (US);
Thomas Lee, Bedminster, NJ (US);
Paul Kurtulik, Somerset, NJ (US);
Sekhar Surapaneni, Warren, NJ (US);
Assignee:
Celgene Corporation, Summit, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/107 (2006.01); A61K 9/10 (2006.01); A61K 31/4045 (2006.01); A61K 47/38 (2006.01); A61K 9/00 (2006.01); A61K 31/4035 (2006.01); A61K 47/20 (2006.01); A61K 47/22 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1075 (2013.01); A61K 9/0053 (2013.01); A61K 9/10 (2013.01); A61K 31/4035 (2013.01); A61K 31/4045 (2013.01); A61K 47/20 (2013.01); A61K 47/22 (2013.01); A61K 47/38 (2013.01); Y10S 977/773 (2013.01); Y10S 977/906 (2013.01);
Abstract
Provided are compositions and methods for preparation and administration of an oral nanosuspension of a poorly soluble drug with improved bioavailability. The method is optimized through microfluidization process with water soluble polymeric excipients in the absence of surfactants.