The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
Jul. 03, 2014
Multiple-pulse pumping for enhanced fluorescence detection and molecular imaging in cells and tissue
University of North Texas Health Science Center, Fort Worth, TX (US);
Texas Christian University, Fort Worth, TX (US);
Ryan M. Rich, Hurst, TX (US);
Ignacy Gryczynski, Fort Worth, TX (US);
Julian Borejdo, Dallas, TX (US);
Zygmunt Gryczynski, Fort Worth, TX (US);
University of North Texas Health Science Center at Fort Worth, Fort Worth, TX (US);
Texas Christian University, Fort Worth, TX (US);
Abstract
The present invention includes a method and system for enhancing the signal-to-noise ratio in emission detection comprising: selecting a probe capable of at least one of fluorescence, phosphorescence, or delayed fluorescence in or about a sample that comprises interfering background signal; and exposing the probe to one or more controllable bursts, each burst comprising two or more pulses, wherein the one or more controllable bursts of high repetition energy pulses enhance the signal from the probe above that of the background signal.