The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
Oct. 15, 2015
Applicant:
Pfenex Inc., San Diego, CA (US);
Inventors:
Jeffrey Allen, Poway, CA (US);
Ping-Hua Feng, San Diego, CA (US);
Anant Patkar, San Diego, CA (US);
Keith L. Haney, San Diego, CA (US);
Lawrence Chew, San Diego, CA (US);
Lei Lei Phokham Sengchanthalangsy, Carlsbad, CA (US);
Assignee:
PFENEX INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/555 (2006.01); A61K 38/21 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); A61K 38/21 (2013.01); C07K 14/555 (2013.01);
Abstract
The present invention relates to the field of recombinant protein production in bacterial hosts. It further relates to extraction of soluble, active recombinant protein from an insoluble fraction without the use of denaturation and without the need for a refolding step. In particular, the present invention relates to a production process for obtaining high levels a soluble recombinant Type 1 interferon protein from a bacterial host.