The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
Aug. 25, 2014
The Regents of the University of Michigan, Ann Arbor, MI (US);
Allegheny-singer Research Institute, Pittsburgh, PA (US);
Colorado State University Research Foundation, Fort Collins, CO (US);
David H. Sherman, Ann Arbor, MI (US);
Garth D. Ehrlich, Pittsburgh, PA (US);
Benjamin Janto, Pittsburgh, PA (US);
Robert M. Williams, Fort Collins, CO (US);
Christopher M. Rath, San Diego, CA (US);
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);
ALLEGHENY-SINGER RESEARCH INSTITUTE, Pittsburgh, PA (US);
COLORADO STATE UNIVERSITY RESEARCH FOUNDATION, Fort Collins, CO (US);
Abstract
The present invention is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS) derived drug and analogs thereof. The invention also discloses polynucleotide sequences useful for heterologous expression in a convenient microbial host for the synthesis of the NRPS derived drug.