The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
Dec. 20, 2013
Applicant:
Greenlight Biosciences, Inc., Medford, MA (US);
Inventors:
William Jeremy Blake, Winchester, MA (US);
James R. Swartz, Menlo Park, CA (US);
Assignee:
GreenLight Biosciences, Inc., Medford, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/16 (2006.01); C12P 7/40 (2006.01); C12P 7/64 (2006.01);
U.S. Cl.
CPC ...
C12P 7/16 (2013.01); C12P 7/40 (2013.01); C12P 7/649 (2013.01); Y02E 50/10 (2013.01); Y02E 50/13 (2013.01);
Abstract
The present disclosure relates, in some aspects, to cell-free methods and systems for large-scale conversion of methane to isobutanol, comprising combining, in a bioreactor at elevated pressure, methane, oxygen, and cell lysates containing methane monooxygenase, methanol dehydrogenase, and enzymes that catalyze the conversion of formaldehyde to isobutanol, to form a cell-free reaction mixture, and incubating under suitable conditions the cell-free reaction to convert methane to isobutanol.