The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
Sep. 22, 2014
Applicant:
Janssen Biotech, Inc., Horsham, PA (US);
Inventors:
Randall Brezski, Spring House, PA (US);
Robert Jordan, Thorton, PA (US);
William Strohl, Spring House, PA (US);
Assignee:
Janssen Biotech, Inc., Horsham, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 16/00 (2006.01); C07K 16/30 (2006.01); C07K 16/22 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); C07K 16/00 (2013.01); C07K 16/22 (2013.01); C07K 16/2863 (2013.01); C07K 16/2887 (2013.01); C07K 16/2896 (2013.01); C07K 16/40 (2013.01); C07K 2317/52 (2013.01); C07K 2317/524 (2013.01); C07K 2317/53 (2013.01); C07K 2317/72 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract
The present invention relates to modified Fc-containing molecules including modified antibodies characterized by increased resistance to host and pathogen-derived proteases, ability to interact with FcγR receptors except with FcγRI, and lack of induction of IL-10 secretion by macrophages, and methods of using and making them.