The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 04, 2017

Filed:

Jun. 20, 2014
Applicant:

Arbor Vita Corporation, Fremont, CA (US);

Inventors:

Peter S. Lu, Sunnyvale, CA (US);

Jonathan David Garman, San Jose, CA (US);

Michael P. Belmares, San Jose, CA (US);

Chamorro Somoza Diaz-Sarmiento, Mountain View, CA (US);

Johannes Schweizer, Mountain View, CA (US);

Assignee:

Arbor Vita Corporation, Fremont, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/08 (2006.01); G01N 33/569 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/084 (2013.01); G01N 33/56983 (2013.01); G01N 33/5748 (2013.01); G01N 33/57411 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/92 (2013.01); G01N 2333/025 (2013.01);
Abstract

The subject invention provides antibodies, including polyclonal and monoclonal antibodies, that bind to E6 proteins from at least three oncogenic strains of HPV. In general, the antibodies bind to amino acids motifs that are conserved between the E6 proteins of different HPV strains, particularly HPV strains 16 and 18. The subject antibodies may be used to detect HPV E6 protein in a sample, and, accordingly, the antibodies find use in a variety of diagnostic applications, including methods of diagnosing cancer. Kits for performing the subject methods and containing the subject antibodies are also provided.


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