The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 04, 2017

Filed:

Mar. 13, 2013
Applicants:

The University of Iowa Research Foundation, Iowa City, IA (US);

The United States of America As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Jack T. Stapleton, Iowa City, IA (US);

Nirjal Bhattarai, Coralville, IA (US);

Jinhua Xiang, Iowa City, IA (US);

James H. McLinden, Coralville, IA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/29 (2006.01); A61K 39/00 (2006.01); C07K 14/005 (2006.01); A61K 38/00 (2006.01); C07K 1/00 (2006.01); A61K 38/16 (2006.01); A61K 45/06 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 38/00 (2013.01); A61K 38/162 (2013.01); A61K 45/06 (2013.01); C07K 1/00 (2013.01); C12N 7/00 (2013.01); C07K 2319/10 (2013.01); C12N 2770/24222 (2013.01); C12N 2770/24233 (2013.01);
Abstract

GB virus C (GBV-C or hepatitis G virus) is a flavivirus that frequently leads to chronic viremia in humans. The invention provides compositions and methods involving GBV-C E2 polypeptides and peptides for use in modulating immune responses, including inhibition inflammation related to pathogenic T-cell activation.


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